http://ije.oxfordjournals.org/content/29/3/405.full#ref-4
In summary, this survey of gastric precancerous lesions in a high-risk population in China revealed associations with blood type A and parental history of gastric cancer, consistent with the role of genetic predisposition. Our findings complement earlier studies in this population implicating the effects of dietary practices, cigarette smoking, Helicobacter pylori infection, and other environmental factors in the progression of precancerous lesions.1,,2 Further studies are needed to elucidate genetic mechanisms and gene-environment interactions in the multi-step process of gastric carcinogenesis.