非特异性损伤引起旳临床反映,  满足 2条原则:  T > 38C or < 36CHR > 90 bpmRR > 20 bpmWCC > 12,000/mm3or < 4,000/mm3or > 10%杆状核
SIRS = systemic inflammatory  response syndrome
SIRS及可疑或明确旳感染
Chest 1992;101:1644.
全身性感染伴器官衰竭
顽固性低血压
SIRS
Sepsis
Severe Sepsis
Septic Shock

Martin GS, Mannino DM, Stephanie Eaton S, et al. The Epidemiology of Sepsis in the United States from 1979 through 2023. N Engl J Med 2023; 348: 1546-54.