摘要翻译：
本文介绍了一种比较分析长核苷酸序列的矩阵方法，将每个序列表示为三个数字二进制序列。这种方法利用核苷酸的生物化学属性，还利用了以Kronecker家族遗传矩阵的一个成员的形式呈现每一组N-二聚体的可能性。由于这种方法，一个长的核苷酸序列可以直观地表示为一个单独的分形镶嵌或另一个二元类型的规则镶嵌。与天然核苷酸序列相比，人工随机序列具有不规则的模式。展示了长核苷酸序列的二元镶嵌的例子，包括人类染色体和青霉素的案例。从格雷码的观点解释核苷酸序列的二元呈现也被检验。分析了矩阵Kronecker乘法产生遗传意义的可能原因。对收到的结果进行了讨论。
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英文标题：
《The matrix method of representation, analysis and classification of long
  genetic sequences》
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作者：
Ivan V. Stepanyan, Sergey V. Petoukhov
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最新提交年份：
2013
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分类信息：

一级分类：Quantitative Biology        数量生物学
二级分类：Other Quantitative Biology        其他定量生物学
分类描述：Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要：
  The article is devoted to a matrix method of comparative analysis of long nucleotide sequences by means of a presentation of each sequence in a form of three digital binary sequences. This method uses biochemical attributes of nucleotides and it also uses a possibility of presentation of every whole set of n-mers in a form of one of members of a Kronecker family of genetic matrices. Due to this method, a long nucleotide sequence can be visually represented as an individual fractal-like mosaic or another regular mosaic of binary type. In contrast to natural nucleotide sequences, artificial random sequences give non-regular patterns. Examples of binary mosaics of long nucleotide sequences are shown, including cases of human chromosomes and penicillins. Interpretation of binary presentations of nucleotide sequences from the point of view of Gray code is also tested. Possible reasons of genetic meaning of Kronecker multiplication of matrices are analyzed. The received results are discussed.
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PDF链接：
https://arxiv.org/pdf/1310.8469