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目录：Spatial Cell Biology
Location, Location, Location
Stella Hurtley
Science 27 November 2009: 1205.
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Perspective
Anatomic Demarcation of Cells: Genes to Patterns
Howard Y. Chang
Science 27 November 2009: 1206-1207.
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Reviews
Actin, a Central Player in Cell Shape and Movement
Thomas D. Pollard and John A. Cooper
Science 27 November 2009: 1208-1212.
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Subcellular mRNA Localization in Animal Cells and Why It Matters
Christine E. Holt and Simon L. Bullock
Science 27 November 2009: 1212-1216.
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The Extracellular Matrix: Not Just Pretty Fibrils
Richard O. Hynes
Science 27 November 2009: 1216-1219.
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Cell Signaling in Space and Time: Where Proteins Come Together and When They’re Apart
John D. Scott and Tony Pawson
Science 27 November 2009: 1220-1224.
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Why and How Bacteria Localize Proteins
L. Shapiro, H. H. McAdams, and R. Losick
Science 27 November 2009: 1225-1228.
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Contents
For all checked items   
This Week in Science
Editor summaries of this week's papers.
Science 27 November 2009: 1159.
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Editorial:
On Incentives for Innovation
Bruce Alberts
Science 27 November 2009: 1163.
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Editors' Choice
Highlights of the recent literature.
Science 27 November 2009: 1164.
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Science Podcast
Science 27 November 2009: 1287.

The show includes speciation by sexual selection, a Medieval Climate Anomaly, the fate of stimulus funding for science, and more.
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New Products
Science 27 November 2009: 1287.

A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.
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News of the Week
Biotechnology
Bankruptcy Won't Stop deCODE, Says Its Founder, Stefánsson
Jocelyn Kaiser
Science 27 November 2009: 1172.

deCODE genetics Inc. filed for bankruptcy last week, but the company will continue operations with a loan from a potential buyer. And its flamboyant leader, Kari Stefánsson, says he hopes to stay on as leader of deCODE's hunt for disease-causing genes.
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Fusion
Schedule Concerns Delay ITER's Go-Ahead
Daniel Clery
Science 27 November 2009: 1172.

The scientific and engineering team building the ITER fusion reactor failed to win an expected endorsement from the project's governing council last week. The council sent the team back to do more work on the proposed construction schedule for the mammoth undertaking.
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Infectious Diseases
Farm Fungicides Linked to Resistance in a Human Pathogen
Martin Enserink
Science 27 November 2009: 1173.

A team of Dutch researchers claims that the massive use of fungicides to protect European orchards, vineyards, and grain fields may be contributing to resistance against drugs used to treat people with life-threatening infections of Aspergillus fumigatus.
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AIDS
Asia Grapples With Unexpected Wave of HIV Infections
Dennis Normile
Science 27 November 2009: 1174.

Across Asia-Pacific, a region so far largely spared the worst of the AIDS epidemic, HIV infections are rising rapidly, primarily among men having sex with men (MSM). With this concern in mind, the U.S. Agency for International Development and the United Nations Development Programme this week sponsored a meeting in Bangkok to bolster the region's HIV prevention, treatment, and care for MSM.
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Newsmaker Interview
Carlos Minc Pushes a Bold Agenda As Brazil's Environment Chief
Antonio Regalado
Science 27 November 2009: 1175.
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Random Samples
Science 27 November 2009: 1171.
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News Focus
Science and the Stimulus
Science and the Stimulus
Jeffrey Mervis
Science 27 November 2009: 1176-1177.

An $18 billion burst of funding from the $787 billion American Recovery and Reinvestment Act is nurturing U.S. research. Where did it go, and is it being spent wisely?
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Science and the Stimulus
Shovel-Ready Science Drives DOE Decisions
Jeffrey Mervis
Science 27 November 2009: 1177-1178.

The Recovery Act enhanced the ability of the Department of Energy's national laboratories to tackle big problems and got the Advanced Research Projects Agency-Energy off to a fast start.
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Science and the Stimulus
NIH Hopes Stimulus Isn't a Roller-Coaster Ride
Jocelyn Kaiser
Science 27 November 2009: 1179-1180.