摘要翻译:
蛋白质是很难单独作用的大分子;它们需要与其他一些蛋白质相互作用才能做到这一点。有许多因素可以调节蛋白质之间的相互作用[4]。在本研究中,我们旨在从定量的角度来了解两种蛋白质ABCB11和ADA的蛋白质-蛋白质相互作用(PPIs)。我们的主要目的之一也是研究调节PPIs的因素,从而在智人和小家鼠两个物种中分别用适当的定量方法区分这些PPIs,了解一种蛋白质与不同物种中不同蛋白质的相互作用。
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英文标题:
《Understanding Functional Protein-Protein Interactions Of ABCB11 And ADA
In Human And Mouse》
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作者:
Antara Sengupta, Sk. Sarif Hassan, Pabitra Pal Choudhury
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最新提交年份:
2015
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分类信息:
一级分类:Quantitative Biology 数量生物学
二级分类:Other Quantitative Biology 其他定量生物学
分类描述:Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要:
Proteins are macromolecules which hardly act alone; they need to make interactions with some other proteins to do so. Numerous factors are there which can regulate the interactions between proteins [4]. Here in this present study we aim to understand Protein -Protein Interactions (PPIs) of two proteins ABCB11 and ADA from quantitative point of view. One of our major aims also is to study the factors that regulate the PPIs and thus to distinguish these PPIs with proper quantification across the two species Homo Sapiens and Mus Musculus respectively to know how one protein interacts with different set of proteins in different species.
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PDF链接:
https://arxiv.org/pdf/1512.04568