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2022-03-05
摘要翻译:
抗生素的滥用和耐药微生物的出现已成为食品工业面临的一大挑战。本工作的目的是利用微流控装置在海藻酸钙基质中微囊化噬菌体UFV-AREG1,并研究其活性和保留效率。将微胶囊加入到丙二醇凝胶中,作为食品工业中的抗菌剂。结果表明,噬菌体包封率高,平均粒径为100~250μm,保留率为82.1μm2%,在凝胶基质中的稳定性为21天。添加到微胶囊噬菌体中的凝胶显示出减少表面细菌污染的效率(表面上无法检测到),其水平与抗菌化学品(酒精70%)相似。因此,在海藻酸钙中微囊化噬菌体并将其应用于食品工业中作为消毒剂是可能的。
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英文标题:
《Evaluation of Microencapsulation of The UFV-AREG1 Bacteriophage in
  Alginate-Ca Microcapsules using Microfluidic Devices》
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作者:
Delaine M. G. Boggionea, La\'is S. Batalha, Marco T. P. Gontijo,
  Maryoris E. S. Lopez, Alvaro V. N. C. Teixeira, Igor J. B. Santos, Regina C.
  S. Mendon\c{c}a
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最新提交年份:
2017
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分类信息:

一级分类:Quantitative Biology        数量生物学
二级分类:Other Quantitative Biology        其他定量生物学
分类描述:Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要:
  The indiscriminate use of antibiotics and the emergence of resistant microorganisms have become a major challenge for the food industry. The purpose of this work was to microencapsulate the bacteriophage UFV-AREG1 in a calcium alginate matrix using microfluidic devices and to study the viability and efficiency of retention. The microcapsules were added to gel of propylene glycol for use as an antimicrobial in the food industry. The technique showed the number of the phage encapsulation, yielding drops with an average 100-250 $\mu$m of diameter, 82.1 $\pm$ 2% retention efficiency and stability in the gel matrix for 21 days. The gel added to the microencapsulated phage showed efficiency (not detectable on the surface) in reducing bacterial contamination on the surface at a similar level to antimicrobial chemicals (alcohol 70%). Therefore, it was possible to microencapsulate bacteriophages in alginate-Ca and apply the microcapsules in gels for use as sanitizers in the food industry.
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PDF链接:
https://arxiv.org/pdf/1707.05621
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