摘要翻译：
采用格子-气元胞自动机(LGCA)模型模拟黏菌中的波纹和聚集。提出了一种有效的表达不同细胞大小、形状和方向的细胞的方法，可以很容易地推广到子实体形成的后期模型中。该LGCA模型旨在研究不应期、最小响应时间、最大振荡周期以及细胞反转与C因子的非线性依赖关系是否是波动的必要假设。结果表明，在不应期为2～3min,最小响应时间为1min,无最大振荡周期的条件下，能较好地再现松散粘球藻的波纹。在高细胞密度时，反转对C因子的非线性依赖是至关重要的。定量模拟表明，当培养物被非信号细胞稀释时，波纹波长的增加完全可以用C-信号细胞密度的降低来解释。这一结果进一步支持了C-信号水平定量地依赖和调节细胞密度的假说。对互穿高密度波的分析表明，存在类似于互穿孤子相移的相移。最后，提出了蜂群、聚集和子实体早期形成的模型。
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英文标题：
《Lattice gas cellular automata model for rippling and aggregation in
  myxobacteria》
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作者：
Mark S. Alber, Yi Jiang and Maria A. Kiskowski
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最新提交年份：
2004
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分类信息：

一级分类：Quantitative Biology        数量生物学
二级分类：Quantitative Methods        定量方法
分类描述：All experimental, numerical, statistical and mathematical contributions of value to biology
对生物学价值的所有实验、数值、统计和数学贡献
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一级分类：Quantitative Biology        数量生物学
二级分类：Other Quantitative Biology        其他定量生物学
分类描述：Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要：
  A lattice-gas cellular automaton (LGCA) model is used to simulate rippling and aggregation in myxobacteria. An efficient way of representing cells of different cell size, shape and orientation is presented that may be easily extended to model later stages of fruiting body formation. This LGCA model is designed to investigate whether a refractory period, a minimum response time, a maximum oscillation period and non-linear dependence of reversals of cells on C-factor are necessary assumptions for rippling. It is shown that a refractory period of 2-3 minutes, a minimum response time of up to 1 minute and no maximum oscillation period best reproduce rippling in the experiments of {\it Myxoccoccus xanthus}. Non-linear dependence of reversals on C-factor is critical at high cell density. Quantitative simulations demonstrate that the increase in wavelength of ripples when a culture is diluted with non-signaling cells can be explained entirely by the decreased density of C-signaling cells. This result further supports the hypothesis that levels of C-signaling quantitatively depend on and modulate cell density. Analysis of the interpenetrating high density waves shows the presence of a phase shift analogous to the phase shift of interpenetrating solitons. Finally, a model for swarming, aggregation and early fruiting body formation is presented.
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PDF链接：
https://arxiv.org/pdf/q-bio/0401014