摘要翻译：
据观察，在与Conspectics的搏斗中持续获胜的雄性小鼠可以抬高尾巴，这与吗啡诱导的斯特劳布尾巴反应非常相似。由于这种反应是阿片激活的一个典型指标，人们提出这类小鼠的阿片能系统是慢性激活的。这种激活似乎是导致攻击成瘾的一个有效因素。为了验证这一假设，我们将连续赢得20场比赛的小鼠与特定动物进行行为敏化程序。mu-阿片受体激动剂吗啡(10mg/kg)的作用在攻击剥夺5天和14天前后，对获胜者的行为进行了露天测试。吗啡对60%的获胜者被剥夺14天攻击性的开阔场地行为的刺激作用比对对照组小鼠的刺激作用强得多。吗啡在剥夺前或剥夺后5天都没有刺激获胜者的行为活动。获胜者被剥夺后的攻击性水平高于被剥夺前。结论是，在获胜者中，穆阿片受体对吗啡的影响变得耐受，并在长期攻击剥夺后变得敏感。根据成瘾理论(Robinson，Berridge，2003)讨论了由于反复胜利而导致的攻击成瘾的发展。
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英文标题：
《Straub tail, the deprivation effect and addiction to aggression》
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作者：
Natalia N. Kudryavtseva
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最新提交年份：
2006
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分类信息：

一级分类：Quantitative Biology        数量生物学
二级分类：Other Quantitative Biology        其他定量生物学
分类描述：Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要：
  It has been observed that male mice who are consistently winning fights with conspecifics can raise their tail, which is very similar to a morphine-induced Straub tail response. Since this response is a typical index of opiate activation, it has been proposed that the opioidergic systems of such mice are chronically activated. This activation appeared to be a potent factor, which leads to addiction to aggression. To check this hypothesis, we exposed the mice who had won 20 fights in succession with conspecifics to a behavioral sensitization procedure. The effects of the mu-opioid receptor agonist morphine (10 mg/kg, i.p.) on the behavior of winners were examined in an open-field test before and after 5- and 14-day deprivation of aggression. Morphine had a much stronger stimulating effect on the open-field behavior of 60 % of the winners deprived of aggression for 14 days than on that of the control mice. Morphine did not stimulate behavioral activity in the winners before or after deprivation for 5 days. The aggression level in the winners was higher after than before deprivation. It has been concluded that, in the winners, the mu-opioid receptors became tolerant to the effects of morphine and became sensitized after long aggression deprivation. The development of addiction to aggression due to repeated victories is discussed in the light of the theory of addiction (Robinson,Berridge, 2003).
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PDF链接：
https://arxiv.org/pdf/q-bio/0602017