摘要翻译：
生物学研究的生理学传统使用简化的描述来分析生物系统，就像工程师使用放大器的“黑匣子”描述一样。简单的模型已经被生理学家使用了很长时间。生理学家已经成功地用一种“面向设备”的方法分析了广泛的生物系统，这种方法类似于工程师用来研究她的设备的方法。这一代人通过结构和（分子）动态分析的强大透镜来观察生物学，这是可以理解的，因为分析的美丽和力量，以及使用这些结构与现有免费软件的方便性。问题是，这些强大的镜头提供了如此大的放大倍率，工程方法是看不到的。高倍率意味着视野有限，因为（空间）动态范围不能涵盖一切。许多生物学家的工作中看不到结构和分子动力学的功能，可能是因为他们计算的结构和分子动力学中不能立即看到功能。对生物学家来说，测量其系统的输入和输出与测量其结构一样重要。至少对一位生理学家来说，这一研究似乎很清楚，假设大多数生物系统是可以用分析工程设备的相同策略进行分析的设备，将会推动这项研究。今天把你的生物制剂当作一个装置来思考，告诉你明天要做什么实验。对我们许多人来说，一个重要的任务是将生理学传统传递给下一代生物物理学家，帮助他们适应分子和原子生物学的新长度、尺度和技术。
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英文标题：
《Living Devices》
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作者：
Bob Eisenberg
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最新提交年份：
2012
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分类信息：

一级分类：Quantitative Biology        数量生物学
二级分类：Other Quantitative Biology        其他定量生物学
分类描述：Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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一级分类：Physics        物理学
二级分类：History and Philosophy of Physics        物理学的历史与哲学
分类描述：History and philosophy of all branches of physics, astrophysics, and cosmology, including appreciations of physicists.
物理学、天体物理学和宇宙学的所有分支的历史和哲学，包括物理学家的赏析。
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英文摘要：
  The physiological tradition of biological research analyzes biological systems using reduced descriptions much as an engineer uses a 'black box' description of an amplifier. Simple models have been used by physiologists for a very long time. Physiologists have successfully analyzed a broad range of biological systems using a 'device-oriented' approach similar to the approach an engineer would use to investigate her devices. The present generation views biology through the powerful lenses of structural and (molecular) dynamic analysis, understandably enough because of the beauty and power of the analysis, and the ease of using these structures with present freely available software. The problem is that these powerful lenses offer such magnification that the engineering approach cannot be seen. High magnification means limited field of view, because the (spatial) dynamic range cannot cover everything. The function of the structures and molecular dynamics cannot be seen in the work of many biologists, probably because function cannot be immediately seen in the structures and molecular dynamics they compute. It is just as important for biologists to measure the inputs and outputs of their systems as it is to measure their structures. It seems clear, at least to one physiologist, that this research will be catalyzed by assuming that most biological systems are devices that can be analyzed with the same strategies one would use to analyze engineering devices. Thinking today about your biological preparation as a device tells you what experiments to do tomorrow. An important task for many of us is to transmit the physiological tradition to the next generation of biophysicists to help them adapt traditional questions to the new length scales and techniques of molecular and atomic biology.
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PDF链接：
https://arxiv.org/pdf/1206.6490