摘要翻译:
为了达到成本效益,生物医学蛋白质必须根据许多因素进行优化。路线图通常用于大型项目,在这里,基于生物信息学分形热力学尺度的描述方法被测试了一个重要的例子,HPV疫苗。2000年以前的老量表被发现产生了不确定的结果,但现代生物信息量表惊人地准确,内部一致性很高,几乎没有歧义。
---
英文标题:
《Minimal Immunogenic Epitopes Have Nine Amino Acids》
---
作者:
J. C. Phillips
---
最新提交年份:
2016
---
分类信息:
一级分类:Quantitative Biology 数量生物学
二级分类:Other Quantitative Biology 其他定量生物学
分类描述:Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
--
---
英文摘要:
To be cost-effective, biomedical proteins must be optimized with regard to many factors. Road maps are customary for large-scale projects, and here descriptive methods based on bioinformatic fractal thermodynamic scales are tested against an important example, HPV vaccine. Older scales from before 2000 are found to yield inconclusive results, but modern bioinformatic scales are amazingly accurate, with a high level of internal consistency, and little ambiguity.
---
PDF链接:
https://arxiv.org/pdf/1607.06835