摘要翻译:
发生在生物体DNA中的核苷酸碱基序列常被视为其构建的共描述。然而,DNA序列中的信息只能被看作是相对于可操作的生化机器的一个共描述,信息以指导构建过程的方式约束着生化机器。事实上,任何一个DNA共描述有效的生化机器本身都是通过对一个相同或非常相似的共描述的机械解释而产生的。用这些术语来说,生命的起源可以被描述为一个引导过程,包括遗传信息的同时积累和机器的产生,机器将其解释为自己构造的指令。在热力学、信息学和自再生自动机的理论框架内讨论了这一问题,特别关注遗传编码的物理化学起源以及一个系统要维持半分裂必须满足的热力学和信息学条件。生命的起源等同于生物半感染
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英文标题:
《Genetic information, physical interpreters and thermodynamics; the
material-informatic basis of biosemiosis》
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作者:
Peter R. Wills
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最新提交年份:
2013
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分类信息:
一级分类:Quantitative Biology 数量生物学
二级分类:Other Quantitative Biology 其他定量生物学
分类描述:Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要:
The sequence of nucleotide bases occurring in an organism's DNA is often regarded as a codescript for its construction. However, information in a DNA sequence can only be regarded as a codescript relative to an operational biochemical machine, which the information constrains in such a way as to direct the process of construction. In reality, any biochemical machine for which a DNA codescript is efficacious is itself produced through the mechanical interpretation of an identical or very similar codescript. In these terms the origin of life can be described as a bootstrap process involving the simultaneous accumulation of genetic information and the generation of a machine that interprets it as instructions for its own construction. This problem is discussed within the theoretical frameworks of thermodynamics, informatics and self-reproducing automata, paying special attention to the physico-chemical origin of genetic coding and the conditions, both thermodynamic and informatic, which a system must fulfil in order for it to sustain semiosis. The origin of life is equated with biosemiosis
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PDF链接:
https://arxiv.org/pdf/1308.2107