摘要翻译:
我们提出了颈连接器摆动模型来研究驱动蛋白的机械力化学耦合机制。得到了不同载荷下速度与ATP浓度的类米氏曲线,与实验结果一致。我们预测米氏常数并不是单调增加的,随着外加力的增加,会发生弹性失稳。
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英文标题:
《Mechanochemical coupling of kinesin studied with the neck linker swing
model》
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作者:
Yaogen Shu and Hualin Shi
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最新提交年份:
2006
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分类信息:
一级分类:Quantitative Biology 数量生物学
二级分类:Other Quantitative Biology 其他定量生物学
分类描述:Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要:
We have proposed the neck linker swing model to investigate the mechanism of mechanochemical coupling of kinesin. The Michaelis-Menten-like curve for velocity vs ATP concentration at different loads has been obtained, which is in agreement with experiments. We have predicted that Michaelis constant doesn't increase monotonically and an elastic instability will happen with increasing of applied force.
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PDF链接:
https://arxiv.org/pdf/q-bio/0601040