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2022-03-06
摘要翻译:
与南部非洲其他地方相比,安哥拉的艾滋病毒流行开始较晚,并稳定在较低的水平。安哥拉人口相对较少,国内生产总值较高,因此能够果断干预,控制艾滋病毒。抗逆转录病毒疗法的有效性、可获得性和可负担性使人们有可能考虑在安哥拉结束艾滋病毒/艾滋病的流行。我们考虑如果没有艺术会发生什么,没有艺术的反事实,对疫情的影响如果艺术保持目前的铺开,目前的计划,如果覆盖面迅速增加,到2015年达到CD4+细胞计数低于350/微升的人的90%,艾滋病毒阳性孕妇都获得终身抗逆转录病毒疗法(选项B+)的影响,这是加速计划,以及根据世界卫生组织2013年指导方针,从2015年开始,到2018年实现抗逆转录病毒疗法的全面覆盖,这是扩大计划。如果安哥拉要实现总统加速计划中的2015年目标,检测服务将需要扩大。必须保证定期、不间断的药物供应。现有的卫生工作人员将需要加强。需要动员和培训社区卫生工作者,以鼓励人们接受检测和治疗,监测进展情况,并支持人们接受治疗;这反过来将有助于减少耻辱和歧视,减少被诊断为艾滋病毒感染者的后续行动,并提高接受治疗者的依从性。必须建立有效的监测和评价系统,必须扩大和改进数据收集,以支持对流行病的当前和未来状况、方案的成功、抗逆转录病毒疗法患者的病毒载量抑制水平和感染发生率作出可靠估计。
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英文标题:
《Responding to the AIDS epidemic in Angola》
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作者:
Brian G. Williams
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最新提交年份:
2014
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分类信息:

一级分类:Quantitative Biology        数量生物学
二级分类:Other Quantitative Biology        其他定量生物学
分类描述:Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要:
  The epidemic of HIV in Angola started later and stabilized at lower levels than elsewhere in southern Africa. With a relatively small population and a high GDP, Angola is in a good position to intervene decisively to control HIV. The effectiveness, availability and affordability of anti-retroviral therapy (ART) make it possible to contemplate ending the epidemic of HIV/AIDS in Angola. We consider what would have happened without ART, the No ART counterfactual, the impact on the epidemic if the current roll-out of ART is maintained, the Current Programme, the impact if coverage is rapidly increased to reach 90% of people with CD4+ cell counts below 350/micro-litre by 2015 and HIV-positive pregnant women are all offered ART for life (Option B+), the Accelerated Programme, and what might be possible under the 2013 guidelines from the World Health Organization, starting in 2015 and reaching full coverage of ART by 2018, the Expanded Programme.If Angola is to reach the 2015 targets in the Presidents Acceleration Plan testing services will need to be expanded. A regular, uninterrupted supply of drugs will have to be assured. Existing health staff will need to be strengthened. Community health workers will need to be mobilized and trained to encourage people to be tested and accept treatment, to monitor progress and to support people on treatment; this in turn will help to reduce stigma and discrimination, loss to follow up of people diagnosed with HIV, and improve adherence for those on treatment. Effective monitoring and evaluation systems will have to be in place and data collection will have to be extended and improved to support the development of reliable estimates of the current and future state of the epidemic, the success of the programme, levels of viral load suppression for those on ART and the incidence of infection.
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PDF链接:
https://arxiv.org/pdf/1401.6430
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