摘要翻译:
研究了人类基因组中碱基间距的分布。分析了人类基因组中一种核苷酸侧翼不同序列长度的出现频率,发现其分布不具有自相似(分形)结构。然而,结果显示了几个特征:(一)短程间距的分布与纯随机序列非常相似;(ii)长程间距分布基本上偏离随机序列分布,表现出较强的长程相关性;(iii)(A,T)碱基与(C,G)碱基间差异显著;(iv)间距分布显示出微小的振荡。
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英文标题:
《Base spacing distribution analysis for human genome》
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作者:
Andrzej Z. G\'orski and Monika Piwowar
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最新提交年份:
2019
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分类信息:
一级分类:Quantitative Biology 数量生物学
二级分类:Other Quantitative Biology 其他定量生物学
分类描述:Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要:
The distribution of bases spacing in human genome was investigated. An analysis of the frequency of occurrence in the human genome of different sequence lengths flanked by one type of nucleotide was carried out showing that the distribution has no self-similar (fractal) structure. The results nevertheless revealed several characteristic features: (i) the distribution for short-range spacing is quite similar to the purely stochastic sequences; (ii) the distribution for long-range spacing essentially deviates from the random sequence distribution, showing strong long-range correlations; (iii) the differences between (A, T) and (C, G) bases are quite significant; (iv) the spacing distribution displays tiny oscillations.
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PDF链接:
https://arxiv.org/pdf/1904.07860