摘要翻译：
禽流感的迅速爆发对未来几年有效疫苗的结果提出了挑战。最近的研究建立了不同的规范来消除流感大流行。这可以通过熟练的实验分析和跟踪最近的强毒株来实现，并可以广泛适用于疫苗效力的有效测试。世界卫生组织(WHO)每年都会公布药物和疫苗的管理情况，以阻止流感在人群中的传播。由于在启动人口方面一再失败，彻底根除流感大流行似乎仍然是一个悬而未决的问题。为了克服目前的情况，需要在理论和实践方面进行高水平的研究，这可以扩大这一领域的范围。最近的进展也使研究人员能够努力开发有效的疫苗来应对新出现的流感类型。只有在流感大流行时在人群中进行标准化疫苗接种，才能彻底改变目前对抗流感病毒的主张。本文从已有的证据和研究中指出了疫苗适应性研究的不足之处，即疫苗即使在启动人群后仍有失败和效力较低的报道。在世界卫生组织公布的疫苗中，给出了检测有效疫苗的简便实验方法。
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英文标题：
《Influenza Virus Vaccine Efficacy Based On Conserved Sequence Alignment》
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作者：
Baby Jerald, T. R. Gopalakrishnan Nair
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最新提交年份：
2012
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分类信息：

一级分类：Quantitative Biology        数量生物学
二级分类：Other Quantitative Biology        其他定量生物学
分类描述：Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要：
  The rapid outbreak of bird flu challenges the outcome of effective vaccine for the upcoming years. The recent research established different norms to eliminate flu pandemics. This can be made possible with skilled experimental analyses and by tracking the recent virulent strain and can be broadly applicable with effective testing of vaccine efficacy. Every year World Health Organization (WHO) reveals the administration of drug and vaccine to counter arrest the spread of flu among the population. As there are recurrent failures in priming the population, the complete eradication of the flu pandemic is still appears to be an unresolved problem. To overcome the current scenario, high level efforts with theoretical and practical research is required and it can enhance the scope in this field. The recent advancements also allow the researchers to endeavor effective vaccine to meet the emerging flu types. Only the standardized vaccination among the population at the time of flu pandemics will revolutionalize the current propositions against influenza virus. This paper shows the deficiencies of vaccine fitness research as there are reported failures and less efficacy of vaccine even after priming the population from referred evidences and studies. It also shows simple experimental approach in detecting the effective vaccine among the vaccines announced by WHO.
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PDF链接：
https://arxiv.org/pdf/1206.1029