摘要翻译:
本讲座总结了我的团队五年来在细胞生物学技术实验设计和实验结果解释方面的主要成果。主要以随机系统理论的ideqas为基础,介绍了实验的理论概念,并与系统论的一般思想进行了对比。在接下来的部分,我介绍了现有的实验,并讨论了它们的信息作用。也就是说,我表明光显微镜可以被设计成提供与电子显微镜相同的分辨率,并且可以用于使用活细胞的实验。我展示了对细胞行为观察进行客观分析的途径。提出了一种新的显微镜设计,它将综合各种方法的优点,并提出了建立具有预测能力的活细胞模型的步骤,以供实际使用
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英文标题:
《Technical performance and interpretation of physical experiment in
problems of cell biology》
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作者:
Dalibor Stys
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最新提交年份:
2010
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分类信息:
一级分类:Quantitative Biology 数量生物学
二级分类:Other Quantitative Biology 其他定量生物学
分类描述:Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要:
The lecture summarises main results of my team over last five years in the field of technical experiment design and interpretation of results of experiments for cell bi-ology. I introduce the theoretical concept of the experiment, based mainly on ideqas of stochastic systems theory, and confront it with general ideas of systems theory. In the next part I introduce available experiments and discuss their information con-tent. Namely, I show that light microscopy may be designed to give resolution com-parable to that of electron microscopy and that may be used for experiments using living cells. I show avenues to objective analysis of cell behavior observation. I pro-pose new microscope design, which shall combine advantages of all methods, and steps to be taken to build a model of living cells with predictive power for practical use
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PDF链接:
https://arxiv.org/pdf/1007.0471