摘要翻译：
我们表明，生物系统中的主动输运过程可以通过在描述随机过程的中尺度上形成的局部平衡描述来理解。这种新方法利用非平衡态热力学建立的方法来解释在这种尺度上发生的不可逆过程，并根据驱动力提供了速率的非线性动力学方程。结果表明，非平衡态热力学方法在生物体系中的应用范围超出了线性范围。本文详细分析了Ca{2+}-ATP酶在三磷酸腺苷水解过程中对Ca{2+}$的输运模型，结果表明，Ca{2+}-ATP酶与三磷酸腺苷水解反应的Gibbs能呈非线性关系。我们的结果统一了热力学和动力学描述，从而为研究生物系统中不同的输运现象开辟了新的视角。
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英文标题：
《Active transport: A kinetic description based on thermodynamic grounds》
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作者：
S. Kjelstrup, J. M. Rubi and D. Bedeaux
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最新提交年份：
2004
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分类信息：

一级分类：Physics        物理学
二级分类：Soft Condensed Matter        软凝聚态物质
分类描述：Membranes, polymers, liquid crystals, glasses, colloids, granular matter
膜，聚合物，液晶，玻璃，胶体，颗粒物质
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一级分类：Physics        物理学
二级分类：Other Condensed Matter        其他凝聚态物质
分类描述：Work in condensed matter that does not fit into the other cond-mat classifications
在不适合其他cond-mat分类的凝聚态物质中工作
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一级分类：Quantitative Biology        数量生物学
二级分类：Other Quantitative Biology        其他定量生物学
分类描述：Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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一级分类：Quantitative Biology        数量生物学
二级分类：Subcellular Processes        亚细胞过程
分类描述：Assembly and control of subcellular structures (channels, organelles, cytoskeletons, capsules, etc.); molecular motors, transport, subcellular localization; mitosis and meiosis
亚细胞结构（通道、细胞器、细胞骨架、囊膜等）的组装和控制；分子马达；转运；亚细胞定位；有丝分裂和减数分裂
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英文摘要：
  We show that active transport processes in biological systems can be understood through a local equilibrium description formulated at the mesoscale, the scale to describe stochastic processes. This new approach uses the method established by nonequilibrium thermodynamics to account for the irreversible processes occurring at this scale and provides nonlinear kinetic equations for the rates in terms of the driving forces. The results show that the application domain of nonequilibrium thermodynamics method to biological systems goes beyond the linear domain. A model for transport of Ca$^{2+}$ by the Ca$^{2+}$-ATPase, coupled to the hydrolysis of adenosine-triphosphate is analyzed in detail showing that it depends on the reaction Gibbs energy in a non-linear way. Our results unify thermodynamic and kinetic descriptions, thereby opening new perspectives in the study of different transport phenomena in biological systems.
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PDF链接：
https://arxiv.org/pdf/cond-mat/0412493