摘要翻译:
在研究免疫系统中观察到的基本特性,以及从更广泛的角度来看,在生物系统中,一些概念已经被数学化或从分析的角度处理,如简并性、鲁棒性、噪声和蝴蝶结结构。除其他外,这些性质似乎统治着系统运行的许多方面,它们之间共享各自的特性,相互交叉,往往成为彼此不可分割的一部分。北野认为,系统生物学需要坚实的原理和性质的理论和方法基础,能够走向统一的观点。现在可以及时尝试统一这些原则的形式化和分析。
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英文标题:
《Towards an unifying perspective of the fundamental properties and
structural principles governing the immune system》
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作者:
Paolo Tieri, Gastone C. Castellani, Claudio Franceschi
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最新提交年份:
2008
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分类信息:
一级分类:Quantitative Biology 数量生物学
二级分类:Other Quantitative Biology 其他定量生物学
分类描述:Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要:
In the study of the basic properties observed in the immune system and, in a broader view, in biological systems, several concepts have already been mathematically formulated or treated in an analytical perspective, such as degeneracy, robustness, noise, and bow tie architecture. These properties, among others, seem to rule many aspects of the system functioning, and share among themselvesseveral characteristics, intersecting each other, and often becoming one the indivisible part of the other. According to Kitano, systems biology needs solid theoretical and methodological foundation of principles and properties, able to lead towards a unified perspective. An effort in unifying the formalization and analysis of these principles can be now timely attempted.
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PDF链接:
https://arxiv.org/pdf/0801.2302