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论坛 计量经济学与统计论坛 五区 计量经济学与统计软件 HLM专版
2054 1
2014-05-03
I am using MLM to examine the levels of craving across eight time points and two conditions. In the final step of the model, which includes both condition and time, I found main effects of time and medication, but no interaction between the two. When I ran t-tests, the two conditions did not differ significantly on their levels of craving. Therefore, I am not quite sure how to interpret this finding. Please let me know if you have any suggestions or ideas. I am obviously happy to answer any follow-up questions.

Kind regards,

Monika

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2014-5-3 05:19:43
Interpreting results so far:  "There is an overall difference between craving between groups averaged across all periods.  There is a difference across time.  The overall interaction with 7 d.f. is not significant."

Other comments:  You do not give enough detail.  So far, it sounds like a repeated measures design, not Multilevel. What are the elements, and what are their Ns?  How strong are those overall effects -- 0.001?  barely 0.05?

It is usually poor form (because it offers relatively little power) to analyze 8 time periods without considering useful contrasts instead of relying on that test across 8 periods.   A 1 d.f.  contrast that contains most of the trend or other differences will have far more power than the 7 d.f.  test among periods.  Testing the specific contrast also answers a specific question, like, "Is there a trend?" -- instead of giving a relatively useless answer like, "There are differences."

You say you "ran t-tests."  I have to guess, so I guess that you ran t-tests at the separate times.  The lack of "significant" tests here,whereas the overall test was significant, shows that you do have marginal power and that you cannot afford to waste power by testing the non-specific hypotheses.

Do you expect a linear time trend?  Was there a pre-intervention Baseline, which should be contrasted to the next period, to test an Intervention effect?  - An Intervention design might deserve a t-test  between 1 and 2 (assuming intervention after 1), to detect a jolt, with a separate test for 2 through 8 that tests for trend that might either return towards Baseline, move away, or stay constant.
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