全部版块 我的主页
论坛 经济学人 二区 外文文献专区
296 0
2022-03-03
摘要翻译:
经典热力学和统计力学描述了无物与无物相互作用的系统。即使是简单流体的高度精炼的理论也不能很好地处理电相互作用、边界条件或流动,如果有的话。电相互作用、边界条件和流动是生命系统的基本特征。没有流动的生命就是死亡,因此需要一种不同的方法来活着研究生物学。复杂流体理论很好地处理了相互作用、边界条件和流动,这可以从它对液晶的成功处理中看出。我主张一般把离子溶液看作复杂的流体,含有作为溶液溶质和组分的微量元素。酶活性位点是某些溶质为反应物的特例。高浓度的蛋白质电荷使溶质挤入酶的活性位点。电场将化学反应与蛋白质和周围溶液中的电荷联系起来。相互作用增强催化和控制生物功能。我怀疑大多数发生在液体中的化学反应也需要用复杂流体理论来处理。这些反应的电子运动发生在一个暂时的高度集中的涨落中,这是一个瞬时的空间不均匀性。这些反应的电子运动(由量子力学描述)与体溶液的电场(有时是空间)耦合。我怀疑电子运动、不均匀性和化学反应(在凝聚相中)需要用复杂流体理论来处理,因为在这个系统中,就像在许多其他系统中一样,所有的东西都与其他的东西相互作用。
---
英文标题:
《Life's Solutions are Complex Fluids. A Mathematical Challenge》
---
作者:
Bob Eisenberg
---
最新提交年份:
2012
---
分类信息:

一级分类:Quantitative Biology        数量生物学
二级分类:Other Quantitative Biology        其他定量生物学
分类描述:Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
--
一级分类:Physics        物理学
二级分类:Soft Condensed Matter        软凝聚态物质
分类描述:Membranes, polymers, liquid crystals, glasses, colloids, granular matter
膜,聚合物,液晶,玻璃,胶体,颗粒物质
--
一级分类:Physics        物理学
二级分类:Biological Physics        生物物理学
分类描述:Molecular biophysics, cellular biophysics, neurological biophysics, membrane biophysics, single-molecule biophysics, ecological biophysics, quantum phenomena in biological systems (quantum biophysics), theoretical biophysics, molecular dynamics/modeling and simulation, game theory, biomechanics, bioinformatics, microorganisms, virology, evolution, biophysical methods.
分子生物物理、细胞生物物理、神经生物物理、膜生物物理、单分子生物物理、生态生物物理、生物系统中的量子现象(量子生物物理)、理论生物物理、分子动力学/建模与模拟、博弈论、生物力学、生物信息学、微生物、病毒学、进化论、生物物理方法。
--

---
英文摘要:
  Classical thermodynamics and statistical mechanics describe systems in which nothing interacts with nothing. Even the highly refined theory of simple fluids does not deal very well with electrical interactions, boundary conditions, or flows, if at all. Electrical interactions, boundary conditions, and flows are essential features of living systems. Life without flow is death and so a different approach is needed to study biology alive. The theory of complex fluids deals with interactions, boundary conditions, and flows quite well as can be seen in its successful treatment of liquid crystals. I advocate treating ionic solutions in general as complex fluids, with microelements that are the solutes and components of the solution. Enzyme active sites are a special case where some solutes are reactants. Solutes are crowded into active sites of enzyme by the high density of protein charges. The electric field links chemical reactions to charges in the protein and surrounding solutions. Interactions potentiate catalysis and control biological function. I suspect that most chemical reactions that occur in liquids also need to be treated by the theory of complex fluids. The electron movements of these reactions occur in a temporary highly concentrated fluctuation, a transient spatial inhomogeneity in the bulk solution. The electron movements of these reactions (described by quantum mechanics) are coupled to the electric (and sometimes steric) fields of the bulk solution. I suspect the electron movements, inhomogeneities, and chemical reaction (in the condensed phase) need to be treated by the theory of complex fluids because everything interacts with everything else, in this system, as in so many others.
---
PDF链接:
https://arxiv.org/pdf/1207.4737
二维码

扫码加我 拉你入群

请注明:姓名-公司-职位

以便审核进群资格,未注明则拒绝

相关推荐
栏目导航
热门文章
推荐文章

说点什么

分享

扫码加好友,拉您进群
各岗位、行业、专业交流群