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2022-03-07
摘要翻译:
心律失常的一些机制可以表现为传导组织均匀区域接触的基本阻滞和反射行为的组成。为了研究这一现象,我们使用了一个可兴奋组织细胞相互作用的公理一维模型。该模型有四个功能参数,它们决定了细胞的功能状态和持续时间。我们表明,同质可兴奋组织的细胞,根据功能间隔持续时间的比值,可以以孤立波传导模式或三种自生模式中的一种模式运作。证明了孤立波通过均匀导电组织边界的传播可以伴随着块反射或多重反射。块和反射是单向现象,在同一边界上不相容。在同质传导组织边界上的透射、阻滞和反射波的系统化规则为设计复杂心率模式的产生机制和分析提供了新的可能性。
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英文标题:
《Study of conduction, block and reflection at the excitable tissues
  boundary in terms of the interval model of action potential》
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作者:
Sergii Kovalchuk (Geolab, Odessa, Ukraine)
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最新提交年份:
2021
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分类信息:

一级分类:Quantitative Biology        数量生物学
二级分类:Other Quantitative Biology        其他定量生物学
分类描述:Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要:
  Some mechanisms of cardiac arrhythmias can be presented as a composition of elementary acts of block and reflection on the contacts of homogeneous areas of the conducting tissue. For study this phenomena we use an axiomatic one-dimensional model of interaction of cells of excitable tissue. The model has four functional parameters that determine the functional states durations of the cell. We show that the cells of a homogeneous excitable tissue, depending on the ratio of the durations of the functional intervals, can operate in the mode of solitary waves conduction or in one of three modes of selfgeneration. It is proved that the propagation of a solitary wave through the boundary of homogeneous conducting tissues can be accompanied by a block or multiplex reflection. Block and reflection are unidirectional phenomena, and there are not compatible on the same boundary. Systematized rules of transmitting, block and reflection waves at the boundary of homogeneous conducting tissues open up new possibilities for design mechanisms of generation and analyzing complex heart rate patterns.
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PDF链接:
https://arxiv.org/pdf/2107.01376
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