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2022-03-09
摘要翻译:
我们讨论了水在DNA-酶相互作用中的桥接作用,并借助于最近的研究结果,即DNA碱基对离域电子之间的伦敦色散力导致了偶极模的形成,这些偶极模可以被textIt{Taq}聚合酶识别。我们描述了PCR中textIt{Taq}活性的高效和精确靶向的动态起源。相互作用耦合、频率、振幅和相位调制的时空分布组成了一种场模式,这种场模式构成了DNA在周围水中的电磁图像,这是聚合酶在DNA水环境中实际识别的结果。用病毒和细菌DNA溶液记录的电磁信号,通过纯水处理来替换DNA模板,从而实现PCR扩增的实验实现,这与量子场的规范理论范式是一致的。
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英文标题:
《Water Bridging Dynamics of Polymerase Chain Reaction in the Gauge Theory
  Paradigm of Quantum Fields》
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作者:
Luc Montagnier, Jamal A\"issa, Antonio Capolupo, Travis J. A.
  Craddock, Philip Kurian, Claude Lavallee, Albino Polcari, Paola Romano,
  Alberto Tedeschi, and Giuseppe Vitiello
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最新提交年份:
2018
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分类信息:

一级分类:Quantitative Biology        数量生物学
二级分类:Other Quantitative Biology        其他定量生物学
分类描述:Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要:
  We discuss the role of water bridging the DNA-enzyme interaction by resorting to recent results showing that London dispersion forces between delocalized electrons of base pairs of DNA are responsible for the formation of dipole modes that can be recognized by \textit{Taq} polymerase. We describe the dynamic origin of the high efficiency and precise targeting of \textit{Taq} activity in PCR. The spatiotemporal distribution of interaction couplings, frequencies, amplitudes, and phase modulations comprise a pattern of fields which constitutes the electromagnetic image of DNA in the surrounding water, which is what the polymerase enzyme actually recognizes in the DNA water environment. The experimental realization of PCR amplification, achieved through replacement of the DNA template by the treatment of pure water with electromagnetic signals recorded from viral and bacterial DNA solutions, is found consistent with the gauge theory paradigm of quantum fields.
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PDF链接:
https://arxiv.org/pdf/1804.02436
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2022-3-9 09:04:12
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