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2022-03-29
摘要翻译:
我们概述了基因组的全局控制体系结构。提出了基因组控制信息理论。介绍了发育控制网络cene(控制基因)的概念。我们区分部分--基因和控制基因或CENE。Cenes由细胞解释和执行,从而直接细胞活动,包括通讯、生长、分裂、分化和多细胞发育。cenome是基因组中的全球发育控制网络。cenome也是cene,由相互联系的子CENes组成,指导生物体的个体发育。生物体的复杂性与细胞学的复杂性有关。与个体发育和进化的相关性被提及。我们引入了通用细胞和通用基因组的概念。
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英文标题:
《On Programs and Genomes》
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作者:
Eric Werner
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最新提交年份:
2011
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分类信息:

一级分类:Quantitative Biology        数量生物学
二级分类:Other Quantitative Biology        其他定量生物学
分类描述:Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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一级分类:Computer Science        计算机科学
二级分类:Computational Engineering, Finance, and Science        计算工程、金融和科学
分类描述:Covers applications of computer science to the mathematical modeling of complex systems in the fields of science, engineering, and finance. Papers here are interdisciplinary and applications-oriented, focusing on techniques and tools that enable challenging computational simulations to be performed, for which the use of supercomputers or distributed computing platforms is often required. Includes material in ACM Subject Classes J.2, J.3, and J.4 (economics).
涵盖了计算机科学在科学、工程和金融领域复杂系统的数学建模中的应用。这里的论文是跨学科和面向应用的,集中在技术和工具,使挑战性的计算模拟能够执行,其中往往需要使用超级计算机或分布式计算平台。包括ACM学科课程J.2、J.3和J.4(经济学)中的材料。
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一级分类:Quantitative Biology        数量生物学
二级分类:Genomics        基因组学
分类描述:DNA sequencing and assembly; gene and motif finding; RNA editing and alternative splicing; genomic structure and processes (replication, transcription, methylation, etc); mutational processes.
DNA测序与组装;基因和基序的发现;RNA编辑和选择性剪接;基因组结构和过程(复制、转录、甲基化等);突变过程。
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英文摘要:
  We outline the global control architecture of genomes. A theory of genomic control information is presented. The concept of a developmental control network called a cene (for control gene) is introduced. We distinguish parts-genes from control genes or cenes. Cenes are interpreted and executed by the cell and, thereby, direct cell actions including communication, growth, division, differentiation and multi-cellular development. The cenome is the global developmental control network in the genome. The cenome is also a cene that consists of interlinked sub-cenes that guide the ontogeny of the organism. The complexity of organisms is linked to the complexity of the cenome. The relevance to ontogeny and evolution is mentioned. We introduce the concept of a universal cell and a universal genome.
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PDF链接:
https://arxiv.org/pdf/1110.5265
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