摘要翻译：
目的：一个自动解释EEGs的临床决策支持工具可以缩短诊断时间，增强实时应用，如ICU监护。临床医生指出，敏感度为95%，特异性低于5%是临床接受的最低要求。提出了一种基于大数据和机器学习原理的高性能分类系统。方法：提出了一种基于隐马尔可夫模型(HMM)的序列解码和基于深度学习网络的后处理的混合机器学习系统。这些算法使用TUH EEG语料库进行训练和评估，该语料库是世界上最大的临床EEG数据公开数据库。结果：我们的方法提供了90%以上的敏感性和5%以下的特异性。该系统检测三种临床感兴趣的事件：（1）尖峰和/或尖波，(2)周期性偏侧性癫痫样放电，(3)全身性周期性癫痫样放电。它还检测到用于建模背景噪声的三个事件：（1）伪影，(2)眼球运动（3）背景。结论：HMM/Deep learning混合系统可以提供低误报率的脑电事件检测，使自动分析成为临床医生可行的选择。意义：TUH EEG语料库使高数据消耗的机器学习算法应用于EEG分析。性能正在接近临床接受的实时应用。
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英文标题：
《Automatic Analysis of EEGs Using Big Data and Hybrid Deep Learning
  Architectures》
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作者：
Meysam Golmohammadi, Amir Hossein Harati Nejad Torbati, Silvia Lopez
  de Diego, Iyad Obeid, and Joseph Picone
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最新提交年份：
2017
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分类信息：

一级分类：Computer Science        计算机科学
二级分类：Machine Learning        机器学习
分类描述：Papers on all aspects of machine learning research (supervised, unsupervised, reinforcement learning, bandit problems, and so on) including also robustness, explanation, fairness, and methodology. cs.LG is also an appropriate primary category for applications of machine learning methods.
关于机器学习研究的所有方面的论文（有监督的，无监督的，强化学习，强盗问题，等等），包括健壮性，解释性，公平性和方法论。对于机器学习方法的应用，CS.LG也是一个合适的主要类别。
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一级分类：Electrical Engineering and Systems Science        电气工程与系统科学
二级分类：Signal Processing        信号处理
分类描述：Theory, algorithms, performance analysis and applications of signal and data analysis, including physical modeling, processing, detection and parameter estimation, learning, mining, retrieval, and information extraction. The term "signal" includes speech, audio, sonar, radar, geophysical, physiological, (bio-) medical, image, video, and multimodal natural and man-made signals, including communication signals and data. Topics of interest include: statistical signal processing, spectral estimation and system identification; filter design, adaptive filtering / stochastic learning; (compressive) sampling, sensing, and transform-domain methods including fast algorithms; signal processing for machine learning and machine learning for signal processing applications; in-network and graph signal processing; convex and nonconvex optimization methods for signal processing applications; radar, sonar, and sensor array beamforming and direction finding; communications signal processing; low power, multi-core and system-on-chip signal processing; sensing, communication, analysis and optimization for cyber-physical systems such as power grids and the Internet of Things.
信号和数据分析的理论、算法、性能分析和应用，包括物理建模、处理、检测和参数估计、学习、挖掘、检索和信息提取。“信号”一词包括语音、音频、声纳、雷达、地球物理、生理、（生物）医学、图像、视频和多模态自然和人为信号，包括通信信号和数据。感兴趣的主题包括：统计信号处理、谱估计和系统辨识；滤波器设计；自适应滤波/随机学习；（压缩）采样、传感和变换域方法，包括快速算法；用于机器学习的信号处理和用于信号处理应用的机器学习；网络与图形信号处理；信号处理中的凸和非凸优化方法；雷达、声纳和传感器阵列波束形成和测向；通信信号处理；低功耗、多核、片上系统信号处理；信息物理系统的传感、通信、分析和优化，如电网和物联网。
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一级分类：Quantitative Biology        数量生物学
二级分类：Neurons and Cognition        神经元与认知
分类描述：Synapse, cortex, neuronal dynamics, neural network, sensorimotor control, behavior, attention
突触，皮层，神经元动力学，神经网络，感觉运动控制，行为，注意
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一级分类：Statistics        统计学
二级分类：Machine Learning        机器学习
分类描述：Covers machine learning papers (supervised, unsupervised, semi-supervised learning, graphical models, reinforcement learning, bandits, high dimensional inference, etc.) with a statistical or theoretical grounding
覆盖机器学习论文（监督，无监督，半监督学习，图形模型，强化学习，强盗，高维推理等）与统计或理论基础
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英文摘要：
  Objective: A clinical decision support tool that automatically interprets EEGs can reduce time to diagnosis and enhance real-time applications such as ICU monitoring. Clinicians have indicated that a sensitivity of 95% with a specificity below 5% was the minimum requirement for clinical acceptance. We propose a highperformance classification system based on principles of big data and machine learning. Methods: A hybrid machine learning system that uses hidden Markov models (HMM) for sequential decoding and deep learning networks for postprocessing is proposed. These algorithms were trained and evaluated using the TUH EEG Corpus, which is the world's largest publicly available database of clinical EEG data. Results: Our approach delivers a sensitivity above 90% while maintaining a specificity below 5%. This system detects three events of clinical interest: (1) spike and/or sharp waves, (2) periodic lateralized epileptiform discharges, (3) generalized periodic epileptiform discharges. It also detects three events used to model background noise: (1) artifacts, (2) eye movement (3) background. Conclusions: A hybrid HMM/deep learning system can deliver a low false alarm rate on EEG event detection, making automated analysis a viable option for clinicians. Significance: The TUH EEG Corpus enables application of highly data consumptive machine learning algorithms to EEG analysis. Performance is approaching clinical acceptance for real-time applications.
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PDF链接：
https://arxiv.org/pdf/1712.09771