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2022-03-06
摘要翻译:
背景:胎儿临产期脑电图(fEEG)的可行性研究始于20世纪40年代初。到20世纪70年代,产时fEEG监测对诊断和预后有明显的好处,但直到今天,这种监测技术仍然是一个好奇心。目的:我们的目的是回顾报道使用fEEG的研究,包括从解释fEEG模式对分娩时宫缩反应的见解。我们还使用了从临床研究中收集的最相关的信息,为在分娩和分娩单元的独特环境中登记提供建议。数据来源:PubMed。合格标准:搜索策略为:(“胎儿”[网格术语]或“胎儿”[所有字段]或“胎儿”[所有字段])和(“脑电图”[网格术语]或“脑电图”[所有字段]或“脑电图”[所有字段])和(临床试验[ptyp]和“人类”[网格术语])。因为fEEG的研究是国际性的,我们包括了英语、法语、德语和俄语的研究。结果:从筛选的256项研究中,最终有40项纳入定性分析。我们总结并报告fEEG的特点,这些特点清楚地表明它有可能作为分娩过程中胎儿大脑健康的直接生物标志物,辅助胎儿心率监测。然而,临床前瞻性研究还需要进一步确立fEEG监测产时的效用。我们确定了临床研究设计可能成功地将这种产时监测模式带到床边。局限性:尽管在临床队列和动物模型方面进行了80年的研究,但产时fEEG的研究领域仍处于新生阶段,并显示出很大的希望来增强目前实施的电子胎儿监护。
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英文标题:
《Monitoring fetal electroencephalogram intrapartum: a systematic
  literature review》
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作者:
Aude Castel, Yael Frank, John Feltner, Floyd Karp, Catherine Albright,
  Martin G. Frasch
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最新提交年份:
2020
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分类信息:

一级分类:Quantitative Biology        数量生物学
二级分类:Other Quantitative Biology        其他定量生物学
分类描述:Work in quantitative biology that does not fit into the other q-bio classifications
不适合其他q-bio分类的定量生物学工作
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英文摘要:
  Background: Studies about the feasibility of monitoring fetal electroencephalogram (fEEG) during labor began in the early 1940s. By the 1970s, clear diagnostic and prognostic benefits from intrapartum fEEG monitoring were reported, but until today, this monitoring technology has remained a curiosity.   Objectives: Our goal was to review the studies reporting the use of fEEG including the insights from interpreting fEEG patterns in response to uterine contractions during labor. We also used the most relevant information gathered from clinical studies to provide recommendations for enrollment in the unique environment of a labor and delivery unit.   Data sources: PubMed.   Eligibility criteria: The search strategy was: ("fetus"[MeSH Terms] OR "fetus"[All Fields] OR "fetal"[All Fields]) AND ("electroencephalography"[MeSH Terms] OR "electroencephalography"[All Fields] OR "eeg"[All Fields]) AND (Clinical Trial[ptyp] AND "humans"[MeSH Terms]). Because the landscape of fEEG research has been international, we included studies in English, French, German, and Russian.   Results: From 256 screened studies, 40 studies were ultimately included in the qualitative analysis. We summarize and report features of fEEG which clearly show its potential to act as a direct biomarker of fetal brain health during delivery, ancillary to fetal heart rate monitoring. However, clinical prospective studies are needed to further establish the utility of fEEG monitoring intrapartum. We identified clinical study designs likely to succeed in bringing this intrapartum monitoring modality to the bedside.   Limitations: Despite 80 years of studies in clinical cohorts and animal models, the field of research on intrapartum fEEG is still nascent and shows great promise to augment the currently practiced electronic fetal monitoring.
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PDF链接:
https://arxiv.org/pdf/2005.13618
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